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EXO1 is critical for embryogenesis and the DNA damage response in mice with a hypomorphic Nbs1 allele

The maintenance of genome stability is critical for the suppression of diverse human pathologies that include developmental disorders, premature aging, infertility and predisposition to cancer. The DNA damage response (DDR) orchestrates the appropriate cellular responses following the detection of l...

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Publicat a:Nucleic Acids Res
Autors principals: Rein, Katrin, Yanez, Diana A., Terré, Berta, Palenzuela, Lluís, Aivio, Suvi, Wei, Kaichun, Edelmann, Winfried, Stark, Jeremy M., Stracker, Travis H.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551929/
https://ncbi.nlm.nih.gov/pubmed/26160886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv691
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