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Caspase-11 Activation in Response to Bacterial Secretion Systems that Access the Host Cytosol
Inflammasome activation is important for antimicrobial defense because it induces cell death and regulates the secretion of IL-1 family cytokines, which play a critical role in inflammatory responses. The inflammasome activates caspase-1 to process and secrete IL-1β. However, the mechanisms governin...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3675167/ https://ncbi.nlm.nih.gov/pubmed/23762026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003400 |
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