IQGAP1 Is Important for Activation of Caspase-1 in Macrophages and Is Targeted by Yersinia pestis Type III Effector YopM

YopM is a leucine-rich repeat (LRR)-containing effector in several Yersinia species, including Yersinia pestis and Y. pseudotuberculosis. Different Yersinia strains encode distinct YopM isoforms with variable numbers of LRRs but conserved C-terminal tails. A 15-LRR isoform in Y. pseudotuberculosis Y...

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Detalhes bibliográficos
Main Authors: Chung, Lawton K., Philip, Naomi H., Schmidt, Valentina A., Koller, Antonius, Strowig, Till, Flavell, Richard A., Brodsky, Igor E., Bliska, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161239/
https://ncbi.nlm.nih.gov/pubmed/24987096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01402-14
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