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Caspase-1 Activation in Macrophages Infected with Yersinia pestis KIM Requires the Type III Secretion System Effector YopJ

Pathogenic Yersinia species utilize a type III secretion system (T3SS) to translocate effectors called Yersinia outer proteins (Yops) into infected host cells. Previous studies demonstrated a role for effector Yops in the inhibition of caspase-1-mediated cell death and secretion of interleukin-1β (I...

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Detalhes bibliográficos
Main Authors: Lilo, Sarit, Zheng, Ying, Bliska, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519425/
https://ncbi.nlm.nih.gov/pubmed/18559430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01695-07
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