Alveolar Macrophages and Neutrophils Are the Primary Reservoirs for Legionella pneumophila and Mediate Cytosolic Surveillance of Type IV Secretion

Legionella pneumophila, an intracellular pathogen responsible for the severe pneumonia Legionnaires' disease, uses its dot/icm-encoded type IV secretion system (T4SS) to translocate effector proteins that promote its survival and replication into the host cell cytosol. However, by introducing b...

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Detalhes bibliográficos
Main Authors: Copenhaver, Alan M., Casson, Cierra N., Nguyen, Hieu T., Fung, Thomas C., Duda, Matthew M., Roy, Craig R., Shin, Sunny
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187856/
https://ncbi.nlm.nih.gov/pubmed/25092908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01891-14
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