Alveolar Macrophages and Neutrophils Are the Primary Reservoirs for Legionella pneumophila and Mediate Cytosolic Surveillance of Type IV Secretion

Legionella pneumophila, an intracellular pathogen responsible for the severe pneumonia Legionnaires' disease, uses its dot/icm-encoded type IV secretion system (T4SS) to translocate effector proteins that promote its survival and replication into the host cell cytosol. However, by introducing b...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Copenhaver, Alan M., Casson, Cierra N., Nguyen, Hieu T., Fung, Thomas C., Duda, Matthew M., Roy, Craig R., Shin, Sunny
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2014
Pynciau:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187856/
https://ncbi.nlm.nih.gov/pubmed/25092908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01891-14
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