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IL-1R signaling enables bystander cells to overcome bacterial blockade of host protein synthesis

The innate immune system is critical for host defense against microbial pathogens, yet many pathogens express virulence factors that impair immune function. Here, we used the bacterial pathogen Legionella pneumophila to understand how the immune system successfully overcomes pathogen subversion mech...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Copenhaver, Alan M., Casson, Cierra N., Nguyen, Hieu T., Duda, Matthew M., Shin, Sunny
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475993/
https://ncbi.nlm.nih.gov/pubmed/26034289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1501289112
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