Short PEG-Linkers Improve the Performance of Targeted, Activatable Monoclonal Antibody-Indocyanine Green Optical Imaging Probes

The ability to switch optical imaging probes from the quenched (off) to the active state (on) has greatly improved target to background ratios. The optimal activation efficiency of an optical probe depends on complete quenching before activation and complete de-quenching after activation. For instan...

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Bibliografiske detaljer
Main Authors: Sano, Kohei, Nakajima, Takahito, Miyazaki, Kiminori, Ohuchi, Yuya, Ikegami, Takashi, Choyke, Peter L., Kobayashi, Hisataka
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674550/
https://ncbi.nlm.nih.gov/pubmed/23600922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc400050k
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