Short PEG-Linkers Improve the Performance of Targeted, Activatable Monoclonal Antibody-Indocyanine Green Optical Imaging Probes

The ability to switch optical imaging probes from the quenched (off) to the active state (on) has greatly improved target to background ratios. The optimal activation efficiency of an optical probe depends on complete quenching before activation and complete de-quenching after activation. For instan...

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Библиографические подробности
Главные авторы: Sano, Kohei, Nakajima, Takahito, Miyazaki, Kiminori, Ohuchi, Yuya, Ikegami, Takashi, Choyke, Peter L., Kobayashi, Hisataka
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674550/
https://ncbi.nlm.nih.gov/pubmed/23600922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc400050k
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