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Activatable fluorescent cys-diabody conjugated with indocyanine green derivative: consideration of fluorescent catabolite kinetics on molecular imaging

Antibody fragments including diabodies have more desirable pharmacokinetic characteristics than whole antibodies. An activatable optical imaging probe based on a cys-diabody targeting prostate-specific membrane antigen conjugated with the near-infrared fluorophore, indocyanine green (ICG), was desig...

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Detalhes bibliográficos
Main Authors: Sano, Kohei, Nakajima, Takahito, Ali, Towhid, Bartlett, Derek W., Wu, Anna M., Kim, Insook, Paik, Chang H., Choyke, Peter L., Kobayashi, Hisataka
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Photo-Optical Instrumentation Engineers 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677842/
https://ncbi.nlm.nih.gov/pubmed/23752742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.18.10.101304
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