লোডিং...
Aggregation of polyQ-extended proteins is promoted by interaction with their natural coiled-coil partners
Polyglutamine (polyQ) diseases are genetically inherited neurodegenerative disorders. They are caused by mutations that result in polyQ expansions of particular proteins. Mutant proteins form intranuclear aggregates, induce cytotoxicity and cause neuronal cell death. Protein interaction data suggest...
সংরক্ষণ করুন:
| প্রধান লেখক: | , , , |
|---|---|
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
Blackwell Publishing Ltd
2013
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3674527/ https://ncbi.nlm.nih.gov/pubmed/23483542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201300001 |
| ট্যাগগুলো: |
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