Loading...
Aggregation of polyQ-extended proteins is promoted by interaction with their natural coiled-coil partners
Polyglutamine (polyQ) diseases are genetically inherited neurodegenerative disorders. They are caused by mutations that result in polyQ expansions of particular proteins. Mutant proteins form intranuclear aggregates, induce cytotoxicity and cause neuronal cell death. Protein interaction data suggest...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Publishing Ltd
2013
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3674527/ https://ncbi.nlm.nih.gov/pubmed/23483542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201300001 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|