Clonal Expansion of Mitochondrial DNA Deletions in Multiple Sclerosis

OBJECTIVE: Mitochondrial DNA deletions (Δ-mtDNA) are implicated in the pathogenesis of multiple sclerosis (MS), Parkinson’s disease (PD), Alzheimer’s disease (AD) and ageing. Given the diffuse nature of inflammation in MS, aim of this study was to determine whether Δ-mtDNA caused respiratory deficie...

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Bibliografiske detaljer
Main Authors: Campbell, Graham R, Kraytsberg, Yevgenya, Krishnan, Kim J, Ohno, Nobuhiko, Ziabreva, Iryna, Reeve, Amy, Newcombe, Jia, Reynolds, Richard, Lassmann, Hans, Khrapko, Konstantin, Turnbull, Doug M, Mahad, Don J
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674417/
https://ncbi.nlm.nih.gov/pubmed/22688405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-1001-9
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