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No excess of mitochondrial DNA deletions within muscle in progressive multiple sclerosis

BACKGROUND: Mitochondrial dysfunction is an established feature of multiple sclerosis (MS). We recently described high levels of mitochondrial DNA (mtDNA) deletions within respiratory enzyme-deficient (lacking mitochondrial respiratory chain complex IV with intact complex II) neurons and choroid ple...

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Detalhes bibliográficos
Publicado no:Mult Scler
Main Authors: Campbell, Graham R, Reeve, Amy K, Ziabreva, Iryna, Reynolds, Richard, Turnbull, Doug M, Mahad, Don J
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361476/
https://ncbi.nlm.nih.gov/pubmed/23787892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1352458513490547
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