Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis

Objective Cerebral atrophy is a correlate of clinical progression in multiple sclerosis (MS). Mitochondria are now established to play a part in the pathogenesis of MS. Uniquely, mitochondria harbor their own mitochondrial DNA (mtDNA), essential for maintaining a healthy central nervous system. We e...

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Detalhes bibliográficos
Main Authors: Campbell, Graham R, Ziabreva, Iryna, Reeve, Amy K, Krishnan, Kim J, Reynolds, Richard, Howell, Owen, Lassmann, Hans, Turnbull, Doug M, Mahad, Don J
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2011
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580047/
https://ncbi.nlm.nih.gov/pubmed/21446022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22109
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