Proteolysis of MOB1 by the ubiquitin ligase praja2 attenuates Hippo signalling and supports glioblastoma growth

Human glioblastoma is the most frequent and aggressive form of brain tumour in the adult population. Proteolytic turnover of tumour suppressors by the ubiquitin–proteasome system is a mechanism that tumour cells can adopt to sustain their growth and invasiveness. However, the identity of ubiquitin–p...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Lignitto, Luca, Arcella, Antonietta, Sepe, Maria, Rinaldi, Laura, Delle Donne, Rossella, Gallo, Adriana, Stefan, Eduard, Bachmann, Verena A., Oliva, Maria A., Tiziana Storlazzi, Clelia, L'Abbate, Alberto, Brunetti, Arturo, Gargiulo, Sara, Gramanzini, Matteo, Insabato, Luigi, Garbi, Corrado, Gottesman, Max E., Feliciello, Antonio
Format: Artigo
Jezik:Inglês
Izdano: Nature Pub. Group 2013
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674242/
https://ncbi.nlm.nih.gov/pubmed/23652010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2791
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items