Proteolytic control of neurite outgrowth inhibitor NOGO-A by the cAMP/PKA pathway

Protein kinase A (PKA) controls major aspects of neurite outgrowth and morphogenesis and plays an essential role in synaptic plasticity and memory. However, the molecular mechanism(s) of PKA action on neurite sprouting and activity are still unknown. Here, we report that in response to neurotrophin...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Sepe, Maria, Lignitto, Luca, Porpora, Monia, Delle Donne, Rossella, Rinaldi, Laura, Belgianni, Giuseppe, Colucci, Gianna, Cuomo, Ornella, Viggiano, Davide, Scorziello, Antonella, Garbi, Corrado, Annunziato, Lucio, Feliciello, Antonio
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226093/
https://ncbi.nlm.nih.gov/pubmed/25331889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410274111
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