Application of Antibodies to Neuronally Expressed Nogo-A Increases Neuronal Survival and Neurite Outgrowth

Nogo-A, a glycoprotein expressed in oligodendrocytes and central nervous system myelin, inhibits regeneration after injury. Antibodies against Nogo-A neutralize this inhibitory activity, improve locomotor recovery in spinal cord-injured adult mammals, and promote regrowth/sprouting/saving of damaged...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Nagaraj, Vini, Theis, Thomas, Johal, Anmol Singh, Seth, Arihant, Gore, Jada, Arsha, Neha, Patel, Mukti, Hao, Helen Baixia, Kurian, Nikki, Schachner, Melitta
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7432704/
https://ncbi.nlm.nih.gov/pubmed/32751444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21155417
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