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Notch3 functions as a tumor suppressor by controlling cellular senescence

Notch signaling regulates a broad spectrum of cell fate decisions and differentiation. Both oncogenic and tumor suppressor functions have been demonstrated for Notch signaling. However, little is known about the underlying mechanisms of its tumor suppressor function. Here we report that expression o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cui, Hang, Kong, Yahui, Xu, Mei, Zhang, Hong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674178/
https://ncbi.nlm.nih.gov/pubmed/23610446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3902
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