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Notch3 functions as a tumor suppressor by controlling cellular senescence

Notch signaling regulates a broad spectrum of cell fate decisions and differentiation. Both oncogenic and tumor suppressor functions have been demonstrated for Notch signaling. However, little is known about the underlying mechanisms of its tumor suppressor function. Here we report that expression o...

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Bibliografiske detaljer
Main Authors: Cui, Hang, Kong, Yahui, Xu, Mei, Zhang, Hong
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674178/
https://ncbi.nlm.nih.gov/pubmed/23610446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3902
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