Regulation of Senescence in Cancer and Aging

Senescence is regarded as a physiological response of cells to stress, including telomere dysfunction, aberrant oncogenic activation, DNA damage, and oxidative stress. This stress response has an antagonistically pleiotropic effect to organisms: beneficial as a tumor suppressor, but detrimental by c...

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Bibliographic Details
Main Authors: Kong, Yahui, Cui, Hang, Ramkumar, Charusheila, Zhang, Hong
Format: Artigo
Language:Inglês
Published: SAGE-Hindawi Access to Research 2011
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056284/
https://ncbi.nlm.nih.gov/pubmed/21423549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/963172
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