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Dbf4: The whole is greater than the sum of its parts

Together with cyclin-dependent kinases, the Dbf4-dependent kinase (DDK) is essential to activate the Mcm2-7 helicase and, hence, initiate DNA replication in eukaryotes. Beyond its role as the regulatory subunit of the DDK complex, the Dbf4 protein also regulates the activity of other cell cycle kina...

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Detalhes bibliográficos
Main Authors: Matthews, Lindsay A., Guarné, Alba
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674083/
https://ncbi.nlm.nih.gov/pubmed/23549174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24416
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