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Dbf4: The whole is greater than the sum of its parts

Together with cyclin-dependent kinases, the Dbf4-dependent kinase (DDK) is essential to activate the Mcm2-7 helicase and, hence, initiate DNA replication in eukaryotes. Beyond its role as the regulatory subunit of the DDK complex, the Dbf4 protein also regulates the activity of other cell cycle kina...

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Библиографические подробности
Главные авторы: Matthews, Lindsay A., Guarné, Alba
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674083/
https://ncbi.nlm.nih.gov/pubmed/23549174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24416
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