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Dbf4: The whole is greater than the sum of its parts

Together with cyclin-dependent kinases, the Dbf4-dependent kinase (DDK) is essential to activate the Mcm2-7 helicase and, hence, initiate DNA replication in eukaryotes. Beyond its role as the regulatory subunit of the DDK complex, the Dbf4 protein also regulates the activity of other cell cycle kina...

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Détails bibliographiques
Auteurs principaux: Matthews, Lindsay A., Guarné, Alba
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674083/
https://ncbi.nlm.nih.gov/pubmed/23549174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24416
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