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Dbf4: The whole is greater than the sum of its parts

Together with cyclin-dependent kinases, the Dbf4-dependent kinase (DDK) is essential to activate the Mcm2-7 helicase and, hence, initiate DNA replication in eukaryotes. Beyond its role as the regulatory subunit of the DDK complex, the Dbf4 protein also regulates the activity of other cell cycle kina...

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Autors principals: Matthews, Lindsay A., Guarné, Alba
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674083/
https://ncbi.nlm.nih.gov/pubmed/23549174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24416
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