Tankyrase and the canonical Wnt pathway protect lung cancer cells from EGFR inhibition

Lung cancer is the leading cause of death worldwide. Adenocarcinomas, the most common histological subtype of non-small cell lung cancer (NSCLC), are frequently associated with activating mutations in the epidermal growth factor receptor (EGFR) gene. Although these patients often respond clinically...

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Detalhes bibliográficos
Main Authors: Casás-Selves, Matias, Kim, Jihye, Zhang, Zhiyong, Helfrich, Barbara A., Gao, Dexiang, Porter, Christopher C., Scarborough, Hannah A., Bunn, Paul A., Chan, Daniel C., Tan, Aik Choon, DeGregori, James
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673784/
https://ncbi.nlm.nih.gov/pubmed/22738915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2848
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