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Tankyrase is necessary for canonical Wnt signaling during kidney development

Recent studies utilizing small molecule antagonists have revealed that the poly(ADP-ribose) polymerases (PARPs) Tankyrase 1 and 2 are critical regulators of canonical Wnt signaling in some cellular contexts. However, the absence of any activity during zebrafish embryogenesis suggested that the tanky...

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Detalhes bibliográficos
Main Authors: Karner, Courtney M., Merkel, Calli E, Dodge, Michael, Ma, Zhiqiang, Lu, Jianming, Chen, Chuo, Lum, Lawrence, Carroll, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925040/
https://ncbi.nlm.nih.gov/pubmed/20549720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22340
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