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Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development

The mammalian kidney is composed of thousands of individual epithelial tubules known as nephrons. Deficits in nephron number are associated with myriad diseases ranging from complete organ failure to congenital hypertension. A balance between differentiation and maintenance of a mesenchymal progenit...

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Detalhes bibliográficos
Main Authors: Karner, Courtney M., Das, Amrita, Ma, Zhendong, Self, Michelle, Chen, Chuo, Lum, Lawrence, Oliver, Guillermo, Carroll, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050658/
https://ncbi.nlm.nih.gov/pubmed/21350016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.057646
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