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Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development

The mammalian kidney is composed of thousands of individual epithelial tubules known as nephrons. Deficits in nephron number are associated with myriad diseases ranging from complete organ failure to congenital hypertension. A balance between differentiation and maintenance of a mesenchymal progenit...

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Détails bibliographiques
Auteurs principaux: Karner, Courtney M., Das, Amrita, Ma, Zhendong, Self, Michelle, Chen, Chuo, Lum, Lawrence, Oliver, Guillermo, Carroll, Thomas J.
Format: Artigo
Langue:Inglês
Publié: Company of Biologists 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050658/
https://ncbi.nlm.nih.gov/pubmed/21350016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.057646
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