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High-Affinity Interaction between IKKβ and NEMO
The Ser/Thr-specific IκB kinase (IKK), which comprises IKKα or IKKβ and the regulatory protein NEMO, is at the bottleneck for NF-κB activation. IKK activity relies on interaction between NEMO and IKKα or IKKβ. A conserved region in the C-terminal tail of IKKβ or IKKα (NEMO-binding domain, NBD, resid...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3673718/ https://ncbi.nlm.nih.gov/pubmed/18266324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi702312c |
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