Diabetes increases mortality after myocardial infarction by oxidizing CaMKII

Diabetes increases oxidant stress and doubles the risk of dying after myocardial infarction, but the mechanisms underlying increased mortality are unknown. Mice with streptozotocin-induced diabetes developed profound heart rate slowing and doubled mortality compared with controls after myocardial in...

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Detalhes bibliográficos
Main Authors: Luo, Min, Guan, Xiaoqun, Luczak, Elizabeth D., Lang, Di, Kutschke, William, Gao, Zhan, Yang, Jinying, Glynn, Patric, Sossalla, Samuel, Swaminathan, Paari D., Weiss, Robert M., Yang, Baoli, Rokita, Adam G., Maier, Lars S., Efimov, Igor R., Hund, Thomas J., Anderson, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673230/
https://ncbi.nlm.nih.gov/pubmed/23426181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65268
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