Загрузка...
A mutation at the ATP-binding site of pp60v-src abolishes kinase activity, transformation, and tumorigenicity.
We constructed a mutant, called RSV-SF2, at the ATP-binding site of pp60v-src. In this mutant, lysine-295 is replaced with methionine. SF2 pp60v-src was found to have a half-life similar to that of wild-type pp60v-src and was localized in the membranous fraction of the cell. Rat cells expressing SF2...
Сохранить в:
| Главные авторы: | , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
1985
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC367296/ https://ncbi.nlm.nih.gov/pubmed/3927152 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|