A mutation at the ATP-binding site of pp60v-src abolishes kinase activity, transformation, and tumorigenicity.

Lignende værker

• Structural and functional domains of the Rous sarcoma virus transforming protein (pp60src).
  af: Levinson, A D, et al.
  Udgivet: (1981)
• The protein encoded by the transforming gene of avian sarcoma virus (pp60src) and a homologous protein in normal cells (pp60proto-src) are associated with the plasma membrane.
  af: Courtneidge, S A, et al.
  Udgivet: (1980)
• Characterization of sites for tyrosine phosphorylation in the transforming protein of Rous sarcoma virus (pp60v-src) and its normal cellular homologue (pp60c-src).
  af: Smart, J E, et al.
  Udgivet: (1981)
• Restriction of the in vitro and in vivo tyrosine protein kinase activities of pp60c-src relative to pp60v-src.
  af: Coussens, P M, et al.
  Udgivet: (1985)
• Morphological revertants of an avian sarcoma virus-transformed mammalian cell line exhibit tumorigenicity and contain pp60src.
  af: Lau, A F, et al.
  Udgivet: (1979)