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The protein encoded by the transforming gene of avian sarcoma virus (pp60src) and a homologous protein in normal cells (pp60proto-src) are associated with the plasma membrane.

Oncogenesis by avian sarcoma virus is attributable to a single viral gene (src) which encodes a phosphoprotein (pp60src) with the enzymatic activity of a protein kinase. A closely related protein, pp60proto-src, occurs in uninfected cells from a wide variety of vertebrate species and is presumed to...

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Bibliografiska uppgifter
Huvudupphovsmän: Courtneidge, S A, Levinson, A D, Bishop, J M
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1980
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC349710/
https://ncbi.nlm.nih.gov/pubmed/6253989
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