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The protein encoded by the transforming gene of avian sarcoma virus (pp60src) and a homologous protein in normal cells (pp60proto-src) are associated with the plasma membrane.

Oncogenesis by avian sarcoma virus is attributable to a single viral gene (src) which encodes a phosphoprotein (pp60src) with the enzymatic activity of a protein kinase. A closely related protein, pp60proto-src, occurs in uninfected cells from a wide variety of vertebrate species and is presumed to...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Courtneidge, S A, Levinson, A D, Bishop, J M
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1980
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349710/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6253989/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.7.3783
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