A mutation at the ATP-binding site of pp60v-src abolishes kinase activity, transformation, and tumorigenicity.

類似資料

• Structural and functional domains of the Rous sarcoma virus transforming protein (pp60src).
  著者:: Levinson, A D, 等
  出版事項: (1981)
• The protein encoded by the transforming gene of avian sarcoma virus (pp60src) and a homologous protein in normal cells (pp60proto-src) are associated with the plasma membrane.
  著者:: Courtneidge, S A, 等
  出版事項: (1980)
• Characterization of sites for tyrosine phosphorylation in the transforming protein of Rous sarcoma virus (pp60v-src) and its normal cellular homologue (pp60c-src).
  著者:: Smart, J E, 等
  出版事項: (1981)
• Restriction of the in vitro and in vivo tyrosine protein kinase activities of pp60c-src relative to pp60v-src.
  著者:: Coussens, P M, 等
  出版事項: (1985)
• Morphological revertants of an avian sarcoma virus-transformed mammalian cell line exhibit tumorigenicity and contain pp60src.
  著者:: Lau, A F, 等
  出版事項: (1979)