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LOX-mediated collagen crosslinking is responsible for fibrosis-enhanced metastasis

Tumor metastasis is a highly complex, dynamic and inefficient process involving multiple steps, yet accounts for over 90% of cancer patient deaths. Although it has long been known that fibrotic signals enhance tumor progression and metastasis, the underlying molecular mechanisms are still unclear. I...

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Autors principals: Cox, Thomas R., Bird, Demelza, Baker, Ann-Marie, Barker, Holly E., Ho, Melisa W-Y., Lang, Georgina, Erler, Janine T.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672851/
https://ncbi.nlm.nih.gov/pubmed/23345161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2233
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