Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the pre-metastatic niche

SUMMARY: Tumor cell metastasis is facilitated by “pre-metastatic niches” formed in destination organs by invading bone marrow-derived cells (BMDCs). Lysyl oxidase (LOX) is critical for pre-metastatic niche formation. LOX secreted by hypoxic breast tumor cells accumulates at pre-metastatic sites, cro...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Erler, Janine T., Bennewith, Kevin L., Cox, Thomas R., Lang, Georgina, Bird, Demelza, Koong, Albert, Le, Quynh-Thu, Giaccia, Amato J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050620/
https://ncbi.nlm.nih.gov/pubmed/19111879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2008.11.012
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