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Lysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesis

Identification of key molecules that drive angiogenesis is critical for the development of new modalities for the prevention of solid tumor progression. Using multiple models of colorectal cancer, we show that activity of the extracellular matrix-modifying enzyme lysyl oxidase (LOX) is essential for...

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Autors principals: Baker, Ann-Marie, Bird, Demelza, Welti, Jonathan C., Gourlaouen, Morgane, Lang, Georgina, Murray, Graeme I., Reynolds, Andrew R., Cox, Thomas R., Erler, Janine T.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548904/
https://ncbi.nlm.nih.gov/pubmed/23188504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2447
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