Lysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesis

Identification of key molecules that drive angiogenesis is critical for the development of new modalities for the prevention of solid tumor progression. Using multiple models of colorectal cancer, we show that activity of the extracellular matrix-modifying enzyme lysyl oxidase (LOX) is essential for...

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Main Authors: Baker, Ann-Marie, Bird, Demelza, Welti, Jonathan C., Gourlaouen, Morgane, Lang, Georgina, Murray, Graeme I., Reynolds, Andrew R., Cox, Thomas R., Erler, Janine T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548904/
https://ncbi.nlm.nih.gov/pubmed/23188504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2447
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