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Lysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesis

Identification of key molecules that drive angiogenesis is critical for the development of new modalities for the prevention of solid tumor progression. Using multiple models of colorectal cancer, we show that activity of the extracellular matrix-modifying enzyme lysyl oxidase (LOX) is essential for...

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Detalhes bibliográficos
Main Authors: Baker, Ann-Marie, Bird, Demelza, Welti, Jonathan C., Gourlaouen, Morgane, Lang, Georgina, Murray, Graeme I., Reynolds, Andrew R., Cox, Thomas R., Erler, Janine T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548904/
https://ncbi.nlm.nih.gov/pubmed/23188504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2447
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