Cargando...

Young T Cells Age During a Redirected Anti-Tumor Attack: Chimeric Antigen Receptor-Provided Dual Costimulation is Half the Battle

Adoptive therapy with chimeric antigen receptor (CAR)-redirected T cells showed spectacular efficacy in the treatment of leukemia in recent early phase trials. Patient’s T cells were ex vivo genetically engineered with a CAR, amplified and re-administered to the patient. While T cells mediating the...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Hombach, Andreas A., Abken, Hinrich
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672777/
https://ncbi.nlm.nih.gov/pubmed/23761793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00135
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!