CCN4 induces IL-6 production through αvβ5 receptor, PI3K, Akt, and NF-κB singling pathway in human synovial fibroblasts

INTRODUCTION: Osteoarthritis (OA) is the most common degenerative joint disease that is involved in the degradation of articular cartilage. The exact etiology of OA is not completely understood. CCN4 is related to up-regulation in the cartilage of patients with osteoarthritis. Previous studies have...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Hou, Chun-Han, Tang, Chih-Hsin, Hsu, Chin-Jung, Hou, Sheng-Mon, Liu, Ju-Fang
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672729/
https://ncbi.nlm.nih.gov/pubmed/23343403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4151
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares