Bone marrow-derived Gr1(+) cells can generate a metastasis-resistant microenvironment via induced secretion of thrombospondin-1

Metastatic tumors have been shown to establish permissive microenvironments for metastases via recruitment of bone marrow (BM)- derived cells. Here, we show that metastasis-incompetent tumors are also capable of generating such microenvironments. However, in these situations the otherwise pro-metast...

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Autores principales: Catena, Raúl, Bhattacharya, Nandita, Rayes, Tina El, Wang, Suming, Choi, Hyejin, Gao, Dingcheng, Ryu, Seongho, Joshi, Natasha, Bielenberg, Diane, Lee, Sharrell B., Haukaas, Svein A., Gravdal, Karsten, Halvorsen, Ole J., Akslen, Lars A., Watnick, Randolph S., Mittal, Vivek
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672408/
https://ncbi.nlm.nih.gov/pubmed/23633432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-12-0476
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