Bone marrow-derived Gr1(+) cells can generate a metastasis-resistant microenvironment via induced secretion of thrombospondin-1

Metastatic tumors have been shown to establish permissive microenvironments for metastases via recruitment of bone marrow (BM)- derived cells. Here, we show that metastasis-incompetent tumors are also capable of generating such microenvironments. However, in these situations the otherwise pro-metast...

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Hlavní autoři: Catena, Raúl, Bhattacharya, Nandita, Rayes, Tina El, Wang, Suming, Choi, Hyejin, Gao, Dingcheng, Ryu, Seongho, Joshi, Natasha, Bielenberg, Diane, Lee, Sharrell B., Haukaas, Svein A., Gravdal, Karsten, Halvorsen, Ole J., Akslen, Lars A., Watnick, Randolph S., Mittal, Vivek
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672408/
https://ncbi.nlm.nih.gov/pubmed/23633432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-12-0476
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