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Development of a prosaposin-derived therapeutic cyclic peptide that targets ovarian cancer via the tumor microenvironment

The vast majority of ovarian cancer-related deaths are caused by metastatic dissemination of tumor cells resulting in subsequent organ failure. However, despite our increased understanding of the physiological processes involved in tumor metastasis, there are no clinically approved drugs that have m...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Wang, Suming, Blois, Anna, Rayes, Tina El, Liu, Joyce F., Hirsch, Michelle S., Gravdal, Karsten, Palakurthi, Sangeetha, Bielenberg, Diane R., Akslen, Lars A., Drapkin, Ronny, Mittal, Vivek, Watnick, Randolph S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261358/
https://ncbi.nlm.nih.gov/pubmed/26962158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aad5653
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