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Bone marrow-derived Gr1(+) cells can generate a metastasis-resistant microenvironment via induced secretion of thrombospondin-1

Metastatic tumors have been shown to establish permissive microenvironments for metastases via recruitment of bone marrow (BM)- derived cells. Here, we show that metastasis-incompetent tumors are also capable of generating such microenvironments. However, in these situations the otherwise pro-metast...

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Bibliographic Details
Main Authors: Catena, Raúl, Bhattacharya, Nandita, Rayes, Tina El, Wang, Suming, Choi, Hyejin, Gao, Dingcheng, Ryu, Seongho, Joshi, Natasha, Bielenberg, Diane, Lee, Sharrell B., Haukaas, Svein A., Gravdal, Karsten, Halvorsen, Ole J., Akslen, Lars A., Watnick, Randolph S., Mittal, Vivek
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672408/
https://ncbi.nlm.nih.gov/pubmed/23633432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-12-0476
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