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Rac1 is Required for Matrix Metalloproteinase-13 Production by Chondrocytes in Response to Fibronectin Fragments
OBJECTIVE: Matrix fragments, including fibronectin fragments (Fnf), accumulate during the development of osteoarthritis (OA) stimulating chondrocyte matrix metalloproteinase (MMP) production. The objective of this study was to determine the role of the small GTPase Rac1 in chondrocyte signaling stim...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3672376/ https://ncbi.nlm.nih.gov/pubmed/23460186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.37922 |
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