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Increased Matrix Metalloproteinase-13 Production With Aging by Human Articular Chondrocytes in Response to Catabolic Stimuli

Chondrocyte anabolic activity has been shown to decline with aging, but catabolic activity has received little attention. In this study, the effect of aging on the chondrocyte catabolic response was determined by stimulating isolated human chondrocytes with fibronectin fragments (FN-f) or interleuki...

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Auteurs principaux: Forsyth, Christopher B., Cole, Ada, Murphy, Gillian, Bienias, Julia L., Im, Hee-Jeong, Loeser, Richard F.
Format: Artigo
Langue:Inglês
Publié: 2005
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482465/
https://ncbi.nlm.nih.gov/pubmed/16183949
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