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The Endogenous Production of Reactive Oxygen Species Is Required For Stimulation of Human Articular Chondrocyte MMP Production by Fibronectin Fragments

The objective of the present study was to determine if reactive oxygen species (ROS) are required as secondary messengers for fibronectin fragment stimulated matrix metalloproteinase (MMP) production in human articular chondrocytes. Cultured cells were stimulated with 25μg/ml of the α5β1 integrin-bi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Del Carlo, Marcello, Schwartz, Daniel, Erickson, Elizabeth A., Loeser, Richard F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892212/
https://ncbi.nlm.nih.gov/pubmed/17395008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2007.01.035
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