Transcriptional response of human articular chondrocytes treated with fibronectin fragments: an in vitro model of the osteoarthritis phenotype

OBJECTIVE: Fibronectin is a matrix protein that is fragmented during cartilage degradation in osteoarthritis (OA). Treatment of chondrocytes with fibronectin fragments (FN-f) has been used to model OA in vitro, but the system has not been fully characterized. This study sought to define the transcri...

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Detalhes bibliográficos
Publicado no:Osteoarthritis Cartilage
Main Authors: Reed, Kathleen S. M., Ulici, Veronica, Kim, Cheeho, Chubinskaya, Susan, Loeser, Richard F., Phanstiel, Douglas H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870543/
https://ncbi.nlm.nih.gov/pubmed/33248223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2020.09.006
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