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Revisiting RNA-directed DNA methylation

RNA-directed DNA methylation (RdDM) involves sequence-specific guiding of the de novo methylation machinery to complementary genomic DNA by RNA molecules. It is still elusive whether guide RNAs bind directly to DNA or to nascent transcripts produced from it. Even the nature of the guide RNAs is not...

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Autori principali: Dalakouras, Athanasios, Wassenegger, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672289/
https://ncbi.nlm.nih.gov/pubmed/23324611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.23542
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