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Revisiting RNA-directed DNA methylation

RNA-directed DNA methylation (RdDM) involves sequence-specific guiding of the de novo methylation machinery to complementary genomic DNA by RNA molecules. It is still elusive whether guide RNAs bind directly to DNA or to nascent transcripts produced from it. Even the nature of the guide RNAs is not...

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Detalhes bibliográficos
Main Authors: Dalakouras, Athanasios, Wassenegger, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672289/
https://ncbi.nlm.nih.gov/pubmed/23324611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.23542
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