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Revisiting RNA-directed DNA methylation

RNA-directed DNA methylation (RdDM) involves sequence-specific guiding of the de novo methylation machinery to complementary genomic DNA by RNA molecules. It is still elusive whether guide RNAs bind directly to DNA or to nascent transcripts produced from it. Even the nature of the guide RNAs is not...

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Hlavní autoři: Dalakouras, Athanasios, Wassenegger, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672289/
https://ncbi.nlm.nih.gov/pubmed/23324611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.23542
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